Local media personalities
The Krusty the Clown Show
* Krusty the Clown né Herschel Schmoikel Pinkus Krustofski (Dan Castellaneta), The Tracey Ullman Show shorts, entertainer
o Rabbi Hyman Krustofski (Jackie Mason), "Like Father, Like Clown", rabbi and Krusty's formerly estranged father
o Sophie (Drew Barrymore), "Insane Clown Poppy", Krusty's illegitimate daughter
* Sideshow Mel (Dan Castellaneta), "Itchy & Scratchy & Marge", Melvin Van Horne. Sidekick to Krusty the Clown.
* Sideshow Raheem (Michael Carrington), "I Love Lisa", former "Sideshow".
* Louis "Mr. Teeny" Toot, trained monkey
The Itchy & Scratchy Show
* Itchy (Dan Castellaneta), The Tracey Ullman Show shorts, anthropomorphic blue mouse, main character on The Itchy and Scratchy Show
* Scratchy (Harry Shearer), The Tracey Ullman Show shorts, anthropomorphic black cat, main character on The Itchy and Scratchy Show
* Poochie (Dan Castellaneta), "The Itchy & Scratchy & Poochie Show", anthropomorphic beagle, temporary character on The Itchy and Scratchy Show, voiced by Homer
* Roger Meyers, Jr. (Alex Rocco, Hank Azaria), "Itchy & Scratchy & Marge", chairman of Itchy and Scratchy International
* Roger Meyers, Sr., "Itchy & Scratchy Land", founder of Itchy and Scratchy International
* Chester J. Lampwick (Kirk Douglas), "The Day the Violence Died", creator of Itchy and cartoon violence
* June Bellamy (Tress MacNeille), "The Itchy & Scratchy & Poochie Show", the voice of cartoon characters Itchy and Scratchy
Other television shows
* Kent Brockman né Kenny Brockelstein (Harry Shearer), "Krusty Gets Busted", anchorman for KBBL-TV Channel 6
* Scott Christian (Dan Castellaneta), "Krusty Gets Busted", substitute anchor for Kent Brockman
* Arnie Pye (Dan Castellaneta), "Arnie Pye in the Sky" Channel 6 traffic helicopter reporter.
* Bumblebee Man (Hank Azaria), "Itchy and Scratchy: The Movie", Spanish language television host on KMEX-TV "Canal Ocho".
* Gabbo and his handler Arthur (Hank Azaria), "Krusty Gets Kancelled", television puppet who was cancelled after insulting Springfield on air
* Booberella (Tress MacNeille), "I'm Spelling as Fast as I Can", hosts a program that shows B-movies, along the lines of Elvira or her predecessor, Vampira
* Princess Kashmir (Maggie Roswell), "Homer's Night Out", regular on Springfield Squares
* Godfrey Jones (Harry Shearer), host of an investigative show
* Brad Goodman (Albert Brooks), "Bart's Inner Child", cable network self-help specialist
* Opal (Tress MacNeille), "Ice Cream of Margie (with the Light Blue Hair)", Host of the Opal show.
* Troy McClure (Phil Hartman), "Homer vs. Lisa and the 8th Commandment", washed-up movie star (Character retired due to death of Phil Hartman)
o MacArthur Parker (Jeff Goldblum), "A Fish Called Selma", McClure's agent
* Rainier Luftwaffe Wolfcastle (Harry Shearer), "Bart the Genius", action movie star best known for his character McBain
o Greta, Wolfcastle's daughter
* Declan Desmond (Eric Idle), documentary filmmaker.
* The Space Mutants, The Tracey Ullman Show shorts, stars of such films as The Space Mutants, Revenge of the Space Mutants, and The Space Mutants: The Land Down Under
* The Happy Little Elves, The Tracey Ullman Show shorts, stars of the animated children's movie series
* Bill and Marty (Dan Castellaneta and Harry Shearer respectively), "Bart vs. Thanksgiving", radio team on KBBL-FM
* Jerry Rude (Michael McKean), "Monty Can't Buy Me Love", shock jock and host of "Jerry Rude and the Bathroom Bunch"
* Birchibald "Birch" T. Barlow (Harry Shearer), "Sideshow Bob Roberts", host of conservative call-in show on KBBL-AM
* Bleeding Gums Murphy (Ron Taylor, Daryl L. Coley), "Moaning Lisa", jazz musician, possibly Dr. Hibbert's brother, deceased
* Lurleen Lumpkin (Beverly D'Angelo, Doris Grau), "Colonel Homer", country western singer/songwriter, currently in rehab
* Rachel Jordan (Shawn Colvin) and Kovenant, "Alone Again, Natura-Diddily", Christian rock band
* The Larry Davis Experience, frequent live performers at local functions
* Drederick Tatum (Hank Azaria), "Homer vs. Lisa and the 8th Commandment", professional heavy-weight boxer, convicted felon
* Lucius Sweet (Paul Winfield), "The Homer They Fall", professional boxing promoter, Tatum's manager
* Professional wrestlers Rasputin the Friendly Russian (formerly the Mad Russian), Dr. Hillbilly, the Iron Yuppie, Professor Werner von Brawn, Uncle Slam, Rumblelina, Osama bin Rotten, and "The Secretary of Hate" Colin KaPow
* Captain Lance Murdock (Dan Castellaneta), "Bart the Daredevil", daredevil and stuntman
* The Capital City Goofball (Tom Poston), "Dancin' Homer", baseball mascot and congressman
* Jacques (Albert Brooks), "Life on the Fast Lane", professional bowler